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← Neonatal EEG

Background symmetry and interhemispheric synchrony

Symmetry compares homologous content and voltage; synchrony compares burst onset timing and has a non-linear developmental course.

Criteria & assessment

  • Persistent >2:1 voltage difference between homologous regions, or persistent disparity in frequency or graphoelement distribution, is abnormal asymmetry; fleeting differences may remain normal.
  • A burst pair is synchronous when left and right onsets differ by <=1.5 seconds; report the percentage of synchronous bursts.
  • Near-complete synchrony is expected before roughly 27-29 weeks and again near term; about 70% synchrony may occur around 29-30 weeks and some asynchrony is expected from 30-37 weeks.
  • After 38 weeks PMA, substantial asynchrony is not expected; abnormal asynchrony means a clearly excessive PMA-adjusted proportion of bursts with onset difference >1.5 seconds.
Source · 2012 guideline / 2013 publicationACNS neonatal terminology, official PDF · PDF p. 9 ↗

Editorial draft · clinical review pending